The WHO reports that non-communicable diseases (e.g. cardiovascular diseases, cancer, chronic respiratory diseases and diabetes) cause 71% of all deaths globally. Up to 40% of NCD deaths could be prevented, so there is a clear need for individual-centric, technology-based and evidence-based approaches to early detection and structured care. LifeStylePre combines insights from preventive health settings and clinical research. The resulting solutions will be designed to enable personalised lifestyle advice and compliance monitoring for at-risk subjects with the aim of preventing or delaying the onset of irreversible disease burdens.