Companies are currently investing more in IT cybersecurity and cybersecurity management, than in cybersecurity software for vehicles. However, regulatory initiatives are driving Europe towards being a first mover in these domains, The need is great for upskilling safety engineers, producing (cyber-)security talent, and improving the knowledge and cooperation between firms as well as safety and security engineers. AIS2afe addresses this by innovative measures for integrating the safety and security disciplines through developing AI technology, and methodologies and tools targeting AI technology.